Definition of the problem: The development and use of drugs aimed at a positive influence on the cognitive decline in patients suffering from Alzheimer's disease raises a number of ethical issues. Arguments: Among other things, these issues are concerned with the significance of these drugs for the patient's subjective well-being and quality of life and with aspects of informed consent to the use of these drugs, particularly in connection with their use in scientific medical research. Conclusion: The value and significance (...) of antidementia drugs depends not only on their effect on cognitive decline, but also on their wider significance for patients' quality of life and their primary carers. The subjective experience of those directly involved deserves more attention in research and practice. (shrink)

This article presents an overview ofregulations, guidelines and societal debates ineight member states of the EC about a)embryonic and fetal tissue transplantation(EFTT), and b) the use of human embryonic stemcells (hES cells) for research into celltherapy, including `therapeutic' cloning. Thereappears to be a broad acceptance of EFTT inthese countries. In most countries guidance hasbeen developed. There is a `strong' consensusabout some of the central conditions for `goodclinical practice' regarding EFTT.International differences concern, amongstothers, some of the informed consent issuesinvolved, and the (...) questions whether anintermediary organisation is necessary, whetherthe methods of abortion may be influenced bythe possible use of EFT, and whether EFTTshould only be used for the experimentaltreatment of rare disorders. The potential useof hES cells for research into cell therapy hasgiven a new impetus to the debate about (human)embryo research. The therapeutic prospects withregard to the retrieval and research use of hEScells appear to function as a catalyst for theintroduction of less restrictive regulationsconcerning research with spare embryos, atleast in some European countries. It remains tobe seen whether the prospect of treatingpatients suffering from serious disorders withtransplants produced by therapeutic cloningwill decrease the societal and moral resistanceto allowing the generation of embryos for`instrumental' use. (shrink)

Evolutionary psychology and social constructionism are widely regarded as fundamentally irreconcilable approaches to the social sciences. Focusing on the study of the emotions, we argue that this appearance is mistaken. Much of what appears to be an empirical disagreement between evolutionary psychologists and social constructionists over the universality or locality of emotional phenomena is actually generated by an implicit philosophical dispute resulting from the adoption of different theories of meaning and reference. We argue that once this philosophical dispute is recognized, (...) it can be set to the side. When this is done, it becomes clear that the two approaches to the emotions complement, rather than compete with, one another. (shrink)

Internalism--The view that one can have a reason such as to justify an action only if one is moved to do that action--Cannot account for what a child must learn in order to be moved to keep a promise. Nor can it account for the relevance of the considerations that the child must come to understand in order to understand the wrongness of racism. Therefore there is good reason to think internalism false.

Some of the problems associated with the construction of a manifestly covariant relativistic quantum theory are discussed. A resolution of this problem is given in terms of the off mass shell classical and quantum mechanics of Stueckelberg, Horwitz and Piron. This theory contains many questions of interpretation, reaching deeply into the notions of time, localizability and causality. A proper generalization of the Maxwell theory of electromagnetic interaction, required for the well-posed formulation of dynamical problems of systems with electromagnetic interaction is (...) discussed, and some of the significance of recently found (classical) relativistic chaotic behavior is pointed out. Many results of a technical nature have been achieved in this framework; in this paper, some of these are reviewed, but I shall concentrate on a discussion of the basic ideas and foundations of the theory. (shrink)

One of the notable arguments in the history of philosophy is Descartes' thesis: cogito, ergo sum. However, the question as to the logical nature of that argument has not yet been entirely clarified.

It has been pointed out to me that in my article on ‘The Augustan Rules for Dactylic Verse’ I misrepresented an observation of Maas as reported by Wilamowitz in his Griechische Verskunst, p. 53. Wilamowitz' words are: ‘Wenn Tibull und Ovid den Pentameter so bauen, dass die vorletzte Silbe betont wird, tun sie das nach dem Vorgange gleichzeitiger griechischer Epigrammatiker.’ This means, of course, that the Greek writers mentioned ended with a paroxytone word, not necessarily with a disyllable, as I (...) assumed it to mean, and I apologize for the oversight. (shrink)

Gilbert Ryle in The Concept of Mind pronounced the “official doctrine” regarding the nature of the mind and the body as “hailing chiefly from Descartes.” That doctrine, anathematized by Ryle as “the dogma of the ghost in the machine,” is said to hold that every human being is composed of a body and a mind, that the body is physical whereas the mind is not, and that the mind may continue to exist when the body is destroyed. Ryle’s famous attack (...) on the official doctrine has undoubtedly stimulated Cartesian studies, both in those who wish to understand Descartes better in order to make the defense of the doctrine more effective and in those who wish to attack it, sometimes even with arguments which Ryle himself would have rejected. Occasionally, one reads a reference to “Platonic dualism,” not so much as a clearly defined alternative to Cartesian dualism but rather as an inchoate or loose version of Descartes’ doctrine. A recent exception is Richard Rorty who in the first chapter of his book Philosophy and the Mirror of Nature has insisted on the difference between the Platonic and the Cartesian positions, although it should perhaps be added that his hostility to the former is if anything greater than his hostility to the latter. Without suggesting that there are not obvious similarities in the Platonic and Cartesian versions of dualism, it will perhaps be useful to try to penetrate beneath the slogans in order to get a clearer picture of the arguments which impelled Plato to hold a position the strangeness which was evident even to his contemporaries. (shrink)

Can business humanize its stakeholders? And if so, how does this relate to moral consideration for stakeholders? In this paper we compare two business orientations that are relevant for current business theory and practice: a stakeholder orientation and a profit orientation. We empirically investigate the causal relationships between business orientation, humanization, and moral consideration. We report the results of six experiments, making use of different operationalizations of a stakeholder and profit orientation, different stakeholders, and different participant samples. Our findings support (...) the prediction that individual stakeholders observing a stakeholder-oriented firm see the firm’s other stakeholders as more human than individual stakeholders observing a profit-oriented firm. This humanization, in turn, increases individual stakeholders’ moral consideration for the firm’s other stakeholders. Our findings underscore the importance of humanization for stakeholders’ moral consideration for each other. This paper contributes to a deeper understanding of the firm as a moral community of stakeholders. Specifically, we move away from a focus on managers, and how they can make business more moral. Instead we direct attention to stakeholders, and how business can make these stakeholders more moral. (shrink)